The laws of science point to a creator.
Law #1 of Thermodynamics states that matter and energy can not be created nor destroyed.
Law #2 basically states that all matter and energy runs down. It wears out. It increases in Entropy and becomes useless.
Because of Law #2 we can logically assume the universe had a beginning. If it did not all matter and energy in the universe would have ran down eons ago and there would be nothing but useless energy and matter floating around the cosmos.
So, the Universe MUST have had a beginning, That which had a beginning requires a cause, but matter and energy can not be created.
Therefore the cause of the universe must have been able to defy the laws of Thermodynamics and create matter and energy.
Since we have never observed anything in the universe which can naturally create matter and energy the only logical conclusion would be that a deity powerful enough to call forth matter and energy from nothing exists and created the universe.
God himself requires no origin because he is not a physical being. Not being composed of matter he requires no beginning. Only that which has a beginning requires a cause. He has always existed. No matter what you believe something or someone has to have always existed. It is illogical based on the 2nd law of Thermodynamics to believe that the universe has always existed.
This argument is based on scientific fact. While you may find those who sit around trying to come up with ways something can come from nothing with no help from God you'll always find that their ideas are just that, Ideas. They can not be backed up with fact.